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The Botox Commercial: Song, Cast & What It's For

The "Don't take it lying down" chronic-migraine ads.

By TVPills Editorial Team

Maintained by TVPills Editorial Team · Site updated November 4, 2026 (not a product-label review)

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What you see

Women refuse to lie in a dark room and instead “stand up” to chronic migraine. (This is Botox for chronic migraine — not the cosmetic ads.)

Why you remember it: The defiant “don't take it lying down” / “stand up” message.

Tagline

"Don't take it lying down"

Sources

These public sources support the song, spokesperson, mascot, tagline, or scene identified in this commercial guide.

Searching for this ad?

People look for the Botox commercial using phrases like:

“botox migraine commercial”“don't take it lying down commercial”“botox chronic migraine ad”“botox stand up commercial”“migraine commercial botox”

What is Botox?

Botox (onabotulinumtoxinA) is a prescription medication for chronic migraine. Use category: Chronic migraine. See the official local label for the exact approved uses, eligible patients and limitations.

Unverified catalogue summary (commercial-page indication and description) for Botox in US; not checked against current local product information.

The “Talk to a doctor” buttons are affiliate links to our telehealth partners Sesame and Lyla Health. TVPills may earn a commission. This is not medical advice.

Frequently asked questions

What is the Botox commercial slogan?

The Botox ads are known for the line "Don't take it lying down."

What is Botox used for?

Unverified catalogue summary (identity, indication and description) for Botox in US; not checked against current local product information. Botox (onabotulinumtoxinA) is catalogued as a prescription medication used for chronic migraine. Unverified catalogue summary: Use category: Chronic migraine. See the official local label for the exact approved uses, eligible patients and limitations.

How much does Botox cost?

Prices vary by insurance and pharmacy. See the Botox cost & savings guide on TVPills for typical prices and ways to save.

Is TVPills medical advice?

No. TVPills is an informational reference that helps you identify medications seen in TV advertising. Always talk to a licensed healthcare provider about treatment.