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Mavyret vs Paxlovid

A side-by-side look at two antiviral medications advertised on TV. Informational only — not medical advice.

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Maintained by TVPills Editorial Team · Site updated November 4, 2026 (not a product-label review)

AttributeUS MavyretUS Paxlovid
Generic nameglecaprevir/pibrentasvir

Unverified catalogue summary (Generic name) for Mavyret in US; not checked against current local product information.

nirmatrelvir/ritonavir

Unverified catalogue summary (Generic name) for Paxlovid in US; not checked against current local product information.

Drug classSee official local label

Unverified catalogue summary (Drug class) for Mavyret in US; not checked against current local product information.

See official local label

Unverified catalogue summary (Drug class) for Paxlovid in US; not checked against current local product information.

TreatsHepatitis C

Unverified catalogue summary (Treats) for Mavyret in US; not checked against current local product information.

Mild-to-moderate COVID-19 in adults at high risk for progression to severe disease

Unverified catalogue summary (Treats) for Paxlovid in US; not checked against current local product information.

CategoryAntiviral

Unverified catalogue summary (Category) for Mavyret in US; not checked against current local product information.

Antiviral

Unverified catalogue summary (Category) for Paxlovid in US; not checked against current local product information.

ManufacturerAbbVie

Unverified catalogue summary (Manufacturer) for Mavyret in US; not checked against current local product information.

Pfizer

Unverified catalogue summary (Manufacturer) for Paxlovid in US; not checked against current local product information.

Year approved—

Unverified catalogue summary (Year approved) for Mavyret in US; not checked against current local product information.

—

Unverified catalogue summary (Year approved) for Paxlovid in US; not checked against current local product information.

Catalogue warning levelSafety summary withheld — check official label

Unverified catalogue summary (Catalogue warning level) for Mavyret in US; not checked against current local product information.

Safety summary withheld — check official label

Unverified catalogue summary (Catalogue warning level) for Paxlovid in US; not checked against current local product information.

Est. TV ad spend$80M$60M
Side effects and serious risks—

Unverified catalogue summary (Side effects and serious risks) for Mavyret in US; not checked against current local product information.

—

Unverified catalogue summary (Side effects and serious risks) for Paxlovid in US; not checked against current local product information.

Sources and editorial standards

Use the current DailyMed labels to verify approved uses, boxed warnings, and side effects for each medication. Label results can differ by product, strength, and formulation.

Page updated November 4, 2026; the linked resources have not necessarily been reviewed on this date.

Frequently asked questions

Is Mavyret or Paxlovid better?

This directory does not compare clinical effectiveness or safety. Listing Mavyret and Paxlovid together does not establish shared approved indications, equivalence or suitability as substitutes. Consult the correct local labels and your prescriber.

What's the difference between Mavyret and Paxlovid?

The table shows catalogue identification and estimated advertising information for Mavyret and Paxlovid, not a verified medical comparison. Medical descriptions, mechanisms and safety summaries are withheld.

Which one spends more on TV ads?

Mavyret has the larger estimated TV advertising budget of the two.