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Trintellix vs Latuda

A side-by-side look at two mental health medications advertised on TV. Informational only — not medical advice.

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Maintained by TVPills Editorial Team · Site updated November 4, 2026 (not a product-label review)

AttributeUS TrintellixUS Latuda
Generic namevortioxetine

Unverified catalogue summary (Generic name) for Trintellix in US; not checked against current local product information.

lurasidone

Unverified catalogue summary (Generic name) for Latuda in US; not checked against current local product information.

Drug classSee official local label

Unverified catalogue summary (Drug class) for Trintellix in US; not checked against current local product information.

See official local label

Unverified catalogue summary (Drug class) for Latuda in US; not checked against current local product information.

TreatsMajor depressive disorder

Unverified catalogue summary (Treats) for Trintellix in US; not checked against current local product information.

Schizophrenia and depressive episodes associated with bipolar I disorder

Unverified catalogue summary (Treats) for Latuda in US; not checked against current local product information.

CategoryMental Health

Unverified catalogue summary (Category) for Trintellix in US; not checked against current local product information.

Mental Health

Unverified catalogue summary (Category) for Latuda in US; not checked against current local product information.

ManufacturerTakeda Pharmaceuticals America, Inc. (US marketer; licensed from H. Lundbeck A/S)

Unverified catalogue summary (Manufacturer) for Trintellix in US; not checked against current local product information.

Sumitomo Pharma America, Inc.

Unverified catalogue summary (Manufacturer) for Latuda in US; not checked against current local product information.

Year approved—

Unverified catalogue summary (Year approved) for Trintellix in US; not checked against current local product information.

—

Unverified catalogue summary (Year approved) for Latuda in US; not checked against current local product information.

Catalogue warning levelSafety summary withheld — check official label

Unverified catalogue summary (Catalogue warning level) for Trintellix in US; not checked against current local product information.

Safety summary withheld — check official label

Unverified catalogue summary (Catalogue warning level) for Latuda in US; not checked against current local product information.

Est. TV ad spend$130M$85M
Side effects and serious risks—

Unverified catalogue summary (Side effects and serious risks) for Trintellix in US; not checked against current local product information.

—

Unverified catalogue summary (Side effects and serious risks) for Latuda in US; not checked against current local product information.

Sources and editorial standards

Use the current DailyMed labels to verify approved uses, boxed warnings, and side effects for each medication. Label results can differ by product, strength, and formulation.

Page updated November 4, 2026; the linked resources have not necessarily been reviewed on this date.

Frequently asked questions

Is Trintellix or Latuda better?

This directory does not compare clinical effectiveness or safety. Listing Trintellix and Latuda together does not establish shared approved indications, equivalence or suitability as substitutes. Consult the correct local labels and your prescriber.

What's the difference between Trintellix and Latuda?

The table shows catalogue identification and estimated advertising information for Trintellix and Latuda, not a verified medical comparison. Medical descriptions, mechanisms and safety summaries are withheld.

Which one spends more on TV ads?

Trintellix has the larger estimated TV advertising budget of the two.